Pulmonary Injury

Vaccine-mediated immune responses to experimental pulmonary Cryptococcus gattii infection in mice.

... cytoplasmic (CP) protein preparations to induce protection against experimental pulmonary C. gattii infection in mice. BALB/c mice immunized with C. gattii CW and/or CP protein preparations exhibited a significant reduction in pulmonary fungal burden and prolonged survival following pulmonary challenge with C. gattii. Protection was associated with significantly ... and CP protein preparation resulted in an early increase in pulmonary T cell infiltrates following challenge with C. gattii. Overall, our studies show that C. gattii CW and CP protein preparations contain antigens that may be included in a subunit vaccine to induce prolonged protection against pulmonary C. gattii infection. Citation: Chaturvedi AK, Hameed ... CCL4/MIP-1b, CCL5/regulated upon activation, normal T cell expressed and secreted (RANTES) and tumor necrosis factor-a (TNF-a). pulmonary leukocytes whereas the left lobes of the lungs were processed for cytokine analysis as described below. Pulmonary Leukocyte Isolation Lung tissues were excised on days 7, 14, and 21 post-infection, and subjected to enzymatic
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Long-term follow-up of patients after acute kidney injury: patterns of renal functional recovery.

... | e36388 Renal Recovery after Acute Kidney Injury Figure 2. Progression of the glomerular filtration rate from reference to 60 months after acute kidney injury for patients in groups G1 to G4. GFR: estimated glomerular filtration rate; m: months; ref: reference; AKI: lowest value during the acute kidney injury episode; discharge: hospital discharge. ... with acute kidney injury. N Engl J Med 359: 7–20. Ishani A, Xue JL, Himmelfarb J, Eggers PW, Kimmel PL, et al. (2009) Acute kidney injury increases risk of ESRD among elderly. J Am Soc Nephrol 20: 223–228. Coca SG, Yusuf B, Shlipak MG, Garg AX, Parikh CR (2009) Long-term risk of mortality and other adverse outcomes after acute kidney injury: a systematic review ... and to 7 in G3 (46%), and Figure 1. Flowchart of patients included in the analysis. AKI: acute kidney injury; sCr: serum creatinine. doi:10.1371/journal.pone.0036388.g001 2 May 2012 | Volume 7 | Issue 5 | e36388 Renal Recovery after Acute Kidney Injury Table 1. Main characteristics of the four groups: demographic and clinical data. All N = 84 G1
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Flow Cytometric Quantification of Peripheral Blood Cell β-Adrenergic Receptor Density and Urinary Endothelial Cell-Derived Microparticles in Pulmonary Arterial Hypertension.

... of Health, American Thoracic Society /Pulmonary Association Research grant (PH-07-003 (KA)), and Cleveland Clinic Research Program Committee Pilot Grant (RPC# 2014-1045 (JR)). * asosink@ccf.org Abstract Pulmonary arterial hypertension (PAH) is a heterogeneous disease characterized by severe angiogenic remodeling of the pulmonary artery wall and right ventricular ... York Heart Association; PAH, Pulmonary arterial hypertension; PMN, Polymorphonuclear cells; TAPSE, Tricuspid annular plane systolic excursion; WBC, White blood cells. Introduction Pulmonary arterial hypertension (PAH) is a heterogeneous group of debilitating diseases characterized by hyperproliferative apoptosis-resistant pulmonary artery endothelial ... debilitating diseases characterized by hyperproliferative apoptosis-resistant pulmonary artery endothelial cells contributing to vascular remodeling of the small pulmonary arteries, which results in elevated pulmonary artery blood pressure and right ventricular failure [1–3]. β-adrenergic receptors (βAR) are transmembrane G-protein coupled receptors that are
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Burn injury reduces neutrophil directional migration speed in microfluidic devices.

... burn injury, with potential implications for the development of sepsis [16–23]. Flow cytometry analysis of neutrophils reveals impairments in phagocytosis, bactericidal activity, phago-lysosomal activity, and the oxidative burst within two weeks post -injury [24]. Neutrophils demonstrate impaired adhesion and complement receptor expression after burn injury PLoS ... device to document the impairment of neutrophil migration speed after burn injury with a degree of precision previously unattainable. We found that neutrophil motility is depressed as early as 24 hours after the burn injury and is inhibited the most at three to five days after injury. We found that the degree of neutrophil directional migration speed ... subjects. Comparisons with samples from burn patients revealed impaired directional migration speed starting as early as 24 hours after burn injury, reaching a minimum at 72–120 hours, correlated to the size of the burn injury and potentially serving as an early indicator for concurrent infections. Further characterization of neutrophil chemotaxis using
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γδ T cells are required for pulmonary IL-17A expression after ozone exposure in mice: role of TNFα.

... Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America Abstract Ozone is an air pollutant that causes pulmonary symptoms. In mice, ozone exposure causes pulmonary injury and increases bronchoalveolar lavage macrophages and neutrophils. We have shown that IL-17A is important in the recruitment of neutrophils ... to the 3 May 2014 | Volume 9 | Issue 5 | e97707 IL-17A, cd T Cells, TNFa, and Ozone Figure 1. Effect of cd T cell deficiency on pulmonary inflammation and injury. (A–C) BAL neutrophils, macrophages, and protein; (D) pulmonary Il17a mRNA expression; (E–I) BAL G-CSF, IL-6, IP-10, KC, and MCP-1. Results are mean6SEM of 4–11 mice per group. *p,0.05 versus genotype-matched ... and 5A–C). pulmonary inflammation observed in obese mice after subacute O3 is the result of reduced pulmonary IL-17A+ cd T cells, consequent to reduced IL-23 and IL-6 expression. Inflammatory cell recruitment to the lungs after subacute O3 exposure required cd T cells (Fig. 1A,B). cd T cells have also been shown to be required for the pulmonary inflammation
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Communication of Pulmonary Function Test Results: A Survey of Patient's Preferences.

... 2015 1/8 Communication of Pulmonary Function Test Results adherence to all PLOS ONE policies on sharing data and materials. research is required to develop an efficient method of conveying PFT results that will improve patient satisfaction and health outcomes. Introduction Chronic respiratory diseases such as asthma, chronic obstructive pulmonary disease ... undertaken in the Pulmonary Function Laboratories of the Gold Coast Hospital and Health Service (GCHHS) between May and August 2014. The GCHHS comprises two regional hospitals, the Gold Coast University Hospital (570-bed) and Robina Hospital (300-bed) both PLOS ONE | DOI:10.1371/journal.pone.0126617 May 7, 2015 2/8 Communication of Pulmonary Function ... referral to PFT laboratory; physician diagnosis (i.e. was the patient known to have a chronic respiratory disease); specialisation of the requesting physician (i.e. pulmonary specialist versus non -pulmonary specialist); physician report of the patients PFT results (pattern and severity of abnormality). Statistical Analysis All statistical analyses were performed
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Oligodendrogenesis after Cerebral Ischaemia and Traumatic Brain Injury

... oligodendrocyte damage after TBI, although traumatic axonal injury has been intensively investigated.3,27,28 Loss of myelinating oligodendrocytes exacerbates traumatic axonal injury, because myelinated axons are less vulnerable to damage compared to non-myelinated axons, following fluid percussion injury in the rat.29 Injured oligodendrocytes no longer ... brain injury. J Cereb Blood Flow Metab. 2003;23:263-74. 2. Cui X et al. Chemokine, vascular and therapeutic effects of combination Simvastatin and BMSC treatment of stroke. Neurobiol Dis. 2009;36:35-41. 3. Johnson VE et al. Axonal pathology in traumatic brain injury. Exp Neurol. 2013;246:35-43. 4. Smith DH et al. Therapy development for diffuse axonal injury. ... are required to form myelin sheaths for sprouting axons during brain repair processes after brain injury, because mature oligodendrocytes do not proliferate in the adult brain and injured oligodendrocytes no longer form new myelin sheets.7,12-16 Brain injury induces OPC proliferation, leading to a substantial increase in the number of OPCs. However,
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Hyper-activated pro-inflammatory CD16 monocytes correlate with the severity of liver injury and fibrosis in patients with chronic hepatitis B.

... (Figure 3D). These data suggest that the frequency of peripheral CD16+ monocytes is closely associated with liver injury as indicated by the correlation with ALT levels and that the expression of CD16 on liver macrophages is associated with liver injury as indicated by the correlation with HAI scores in IA patients. Neutrophils are reduced in peripheral ... HBV-induced liver disease. Citation: Zhang J-Y, Zou Z-S, Huang A, Zhang Z, Fu J-L, et al. (2011) Hyper-Activated Pro-Inflammatory CD16+ Monocytes Correlate with the Severity of Liver Injury and Fibrosis in Patients with Chronic Hepatitis B. PLoS ONE 6(3): e17484. doi:10.1371/journal.pone.0017484 Editor: Paulo Ho, Instituto Butantan, Brazil Received July 31, ... for monocyes and macrophage) or anti-myeloperoxidase (MPO, specific for neutrophils) Figure 1. Increased monocytes in peripheral blood and liver positively correlate with liver injury in IA patients. (A) Absolute counts of the peripheral blood monocytes from IT (n = 32), IA (n = 78) patients and healthy controls (n = 38). Each dot represents the value
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... partial atresia caused by fibrous bands as a result of birth injury due to instrumental delivery. Rhinoplasty performed to open-up left nostril and patient relieved of his symptoms and also on cosmetic appearance. KEYWORDS Nasal obstruction, Anterior nares atresia, Nasal atresia, Choanal atresia, Birth injury, Congenital nostril atresia. HOW TO CITE THIS ARTICLE: ... Prabakaran J, Venkataramanan R, Jayagar S, et al. Birth injury related unilateral anterior nares partial fibrous atresia: a rare case report. J. Evid. Based Med. Healthc. 2016; 3(14), 522-523. DOI: 10.18410/jebmh/2016/119 INTRODUCTION: Nasal septal deformities are more commonly reported following birth injury happening during the second stage of labour. ... second stage of labour. In our case an instrumental forceps delivery has caused injury to the nose, resulting in fibrous bands due to healing that has caused left nostril partial fibrous atresia. This case is reported here for its rarity. There is no report of a similar birth injury causing unilateral partial nares atresia in the literature so far. CASE
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Doxycyclin induced esophageal injury: A Case series

... Dicle Tıp Dergisi / Dicle Medical Journal İ. Demiryılmaz et al. Doxycyclin induced esophageal injury 2013; 40 (2): 281-2813 doi: 10.5798/diclemedj.0921.2013.02.0270 CASE REPORT / OLGU SUNUMU Doxycyclin induced esophageal injury: A Case series Doksisikline bağli özefagus hasarları: Olgu serisi İsmail Demiryılmaz1, İsmayil Yılmaz2, ... anti-inflammatory medication: case reports andreview of the literature on pill-induced esophageal injury. South Med J 1986;79:1094-1097. 6. Arısı DS, Göze F, Akbayır N. Doxycyline-induced esophagitis. Turk J Gastroenterol 1999;10:1-3. 7. Bott S. Medication-induced esophageal injury: survey of the literature. Am J Gastroenterol 1987;82:758-763. 8. Akbayır N, Alkım ... drugs without sufficient water and sleeping after medication are more frequent [2,7-11]. The patients in our study had history of taking dugs with less amount of water. Esophagus injury due to these drugs occurring at the middle one third part is known [12-14]. In 4 patients of our study, ulcers were serious and at the middle part and in one at the lower
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Podocyte expression of membrane transporters involved in puromycin aminonucleoside-mediated injury.

... transporter families in maintaining podocyte homeostasis and in the pathogenesis of podocyte injury. Citation: Zennaro C, Rastaldi MP, Pascolo L, Stebel M, Trevisan E, et al. (2013) Podocyte Expression of Membrane Transporters Involved in Puromycin Aminonucleoside-Mediated Injury. PLoS ONE 8(6): e66159. doi:10.1371/journal.pone.0066159 Editor: Hendrik W. van ... Podocyte Expression of Membrane Transporters Involved in Puromycin Aminonucleoside-Mediated Injury Cristina Zennaro1, Maria Pia Rastaldi2, Lorella Pascolo6, Marco Stebel3, Elisa Trevisan3, Mary Artero4, Claudio Tiribelli1,5, Vittorio Di Maso1, Michele Carraro1* 1 Department ... antibiotic, which is the substrate of several transporter families that have been fully characterized in other cellular models [5]. The antibiotic was used in the context of podocyte injury by puromycin aminonucleoside (PA), a small molecule that uses membrane transporters to enter the cell [6], and induces podocyte damage which mimics lesions of PLOS ONE
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Making human neurons from stem cells after spinal cord injury.

... Perspectives Making Human Neurons from Stem Cells after Spinal Cord Injury Natalia Abramova Lowry, Sally Temple* Spinal cord injury (SCI) has been recognized as one of the conditions for which stem cell transplantation might first prove beneficial [1]. After SCI, loss of ... Kanemura Y, Mori H, et al. (2005) Transplantation of human neural stem cells for spinal cord injury in primates. J Neuosci Res 80: 182–190. 4. Vroemen M, Aigner L, Winkler J, Weidner N (2003) Adult neural progenitor cell grafts survive after acute spinal cord injury and integrate along axonal pathways. Eur J Neurosci 18: 743–751. 5. Enzmann GU, Benton ... article. Competing Interests: The authors have declared that no competing interests exist. Citation: Lowry NA, Temple S (2007) Making human neurons from stem cells after spinal cord injury. PLoS Med 4(2): e48. doi:10.1371/journal.pmed.0040048 Copyright: © 2007 Lowry and Temple. This is an open-access article distributed under the terms of the Creative Commons
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Systemic down-regulation of delta-9 desaturase promotes muscle oxidative metabolism and accelerates muscle function recovery following nerve injury.

... Systemic Down-Regulation of Delta-9 Desaturase Promotes Muscle Oxidative Metabolism and Accelerates Muscle Function Recovery following Nerve Injury Ghulam Hussain1,2., Florent Schmitt1,2., Alexandre Henriques1,2, Thiebault Lequeu1,2, Frederique Rene1,2, Franc¸oise Bindler3, Sylvie Dirrig-Grosch1,2, Hugues Oudart4, ... known to induce hypermetabolism and stimulate fatty acid beta-oxidation. Here we investigated whether SCD1 deficiency can affect muscle function and its restoration in response to injury. The genetic ablation of SCD1 was not detrimental per se to muscle function. On the contrary, muscles in SCD1 knockout mice shifted toward a more oxidative metabolism, and ... A, Lequeu T, Rene F, et al. (2013) Systemic Down-Regulation of Delta-9 Desaturase Promotes Muscle Oxidative Metabolism and Accelerates Muscle Function Recovery following Nerve Injury. PLoS ONE 8(6): e64525. doi:10.1371/journal.pone.0064525 Editor: Antonio Musaro, University of Rome La Sapienza, Italy Received January 28, 2013; Accepted April 16, 2013;
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Is there an association between traumatic dental injury and social capital, binge drinking and socioeconomic indicators among schoolchildren?

... DOI:10.1371/journal.pone.0118484 February 26, 2015 5 / 12 Association between Traumatic Dental Injury and Social Capital Table 1. Distribution of 588 12-year-old students according to traumatic dental injury and independent variables, Brazil, 2014. Independent variables Traumatic dental injury Sex Male Female Overjet ≤ 5 mm > 5 mm Lip protection Adequate Inadequate Monthly ... preparation of the manuscript. Competing Interests: The authors have declared that no competing interests exist. Results The prevalence of traumatic dental injury was 29.9% (176/588). Traumatic dental injury was more prevalent among male adolescents (p = 0.010), those with overjet greater than 5 mm (p < 0.001) and those with inadequate lip protection (p ... 1.93 PLOS ONE | DOI:10.1371/journal.pone.0118484 February 26, 2015 1 / 12 Association between Traumatic Dental Injury and Social Capital (95% CI: 1.21–3.06), p = 0.005] remained significantly associated with traumatic dental injury. Conclusions The present findings suggest that a high level of total social capital and trust are not associated
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Abnormal pulmonary artery stiffness in pulmonary arterial hypertension: in vivo study with intravascular ultrasound.

... Kirby KS, et al. (2008) Pulmonary vascular input impedance is a combined measure of pulmonary vascular resistance and stiffness and predicts clinical outcomes better than pulmonary vascular resistance alone in pediatric patients with pulmonary hypertension. Am Heart J 155: 166–174. 12. Tuchscherer HA, Vanderpool RR, Chesler NC (2007) Pulmonary vascular ... associations between compliance and mean pulmonary artery pressure (left); and between distensibility and mean pulmonary artery pressure (right). mPAP, mean pulmonary artery pressure. doi:10.1371/journal.pone.0033331.g004 PLoS ONE | www.plosone.org 5 March 2012 | Volume 7 | Issue 3 | e33331 IVUS Assessment of Pulmonary Artery Stiffness ments ... McGoon MD (2006) Relationship of pulmonary arterial capacitance and mortality in idiopathic pulmonary arterial hypertension. J Am Coll Cardiol 47: 799–803. 6. Mahapatra S, Nishimura RA, Oh JK, McGoon MD (2006) The prognostic value of pulmonary vascular capacitance determined by Doppler echocardiography in patients with pulmonary arterial hypertension.
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Does Dexpantenol Protect the Kidney from Ischemia-Reperfusion Injury?

... Anabilim Dalı, Aydın, Türkiye Abstract ObjectIves: Tissue injury occurs following reperfusion after creation of ischemia. Plenty of chemical agents have been shown to protect from such an injury. We planned to evaluate the protective effect of dexpanthenol (dxp) in ischemia-reperfusion injury. MaterIal and methods: 24 adult rats were used and divided ... scavengers to prevent reperfusion injury. J Surg Res 1991; 51: 60-65 2. Furuichi K, Gao JL, Murphy PM: Chemokine receptor CX3CR1 regulates renal interstitial fibrosis after ischemia-reperfusion injury. Am J Pathol 2006; 169: 372-387 3. Sadis C, Teske G, Stokman: Nicotine protects kidney from renal ischemia/reperfusion injury through the cholinergic ... Attenuation of reperfusion injury by renal ischaemic preconditioning: the role of nitric oxide. BJU Int 2000; 85: 1007-1013 15. Akgur FM, Kilinc K, Aktug T: Reperfusion injury after detorsion of unilateral testicular torsion. Urol Res 1993; 21: 395-399 16. Liu X, Chen H, Zhan B, Xing B, Zhou J, Zhu H, Chen Z: Attenuation of reperfusion injury by renal ischemic
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... abuse, and poor general condition and unknown pre-existing conditions. Indecisiveness is a hanging sword in the way of courage to face head injury and facial injury patients. The prognosis of head injury with facial injury patients depends largely on the preoperative, intraoperative and postoperative care of the patient and decision making at the right ... ISSUE II CRANIOROFACIAL AND HEAD INJURY MANAGEMENT :A RESIDENTS PERSPECTIVE SURYAPRATAP SINGH TOMAR1 MOHAMMAD AKHEEL2 www.acofs.com ABSTRACT Everyday, men, women and children suffer head injuries. A car accident, a fall from height or sports injury can range in severity from concussion to coma. Traumatic Brain Injury (TBI) can be fatal,dangerous ... because of the little creeping knowledge gained from immediate www.acofs.com 19 ACOFS CRANIOROFACIAL AND HEAD INJURY MANAGEMENT - RESIDENT'S PERSPECTIVE VOL I ISSUE II seniors. There is no proper training of head injury management. The clerical filework and the overwork takes a toll on the residents ability. For residents working continuously
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Lung function and incidence of chronic obstructive pulmonary disease after improved cooking fuels and kitchen ventilation: a 9-year prospective cohort study.

... Biomass smoke is associated with the risk of chronic obstructive pulmonary disease (COPD), but few studies have elaborated approaches to reduce the risk of COPD from biomass burning. The purpose of this study was to determine whether improved cooking fuels and ventilation have effects on pulmonary function and the incidence of COPD. Methods and Findings: ... exclusion criteria included a diagnosis of active tuberculosis, asthma, obvious bronchiectasis, cystic fibrosis, interstitial lung disease, pulmonary thromboembolic disease, or malignant tumor; a history of thoracotomy with pulmonary resection, uncontrolled or serious diseases, or other symptoms that could potentially affect the spirometry test; or a plan ... ChiCTR-OCH-12002398 Please see later in the article for the Editors’ Summary. Citation: Zhou Y, Zou Y, Li X, Chen S, Zhao Z, et al. (2014) Lung Function and Incidence of Chronic Obstructive Pulmonary Disease after Improved Cooking Fuels and Kitchen Ventilation: A 9-Year Prospective Cohort Study. PLoS Med 11(3): e1001621. doi:10.1371/journal.pmed.1001621 Academic
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Development of an Arthroscopic Joint Capsule Injury Model in the Canine Shoulder.

... joint capsule injury model in the canine shoulder using arthroscopy, without frank injury to the overlying rotator cuff tendons. We propose use of an all arthroscopic technique in order to minimize the extent of soft tissue injury PLOS ONE | DOI:10.1371/journal.pone.0147949 January 25, 2016 2 / 15 Arthroscopic Joint Capsule Injury Model in ... injury presented herein has the potential to allow investigators to study the role of joint capsule injury, tendon/muscle unloading, and nerve injury? ??in isolation or combination—on the development of rotator cuff pathologies. The data reported here are intended to demonstrate technical feasibility and proof-ofconcept for an isolated joint capsule injury ... that an isolated joint capsule injury model will be associated with pathologic changes in the shoulder joint. We anticipate that a joint capsule injury model can be used in future studies to investigate biochemical and pathologic changes to the shoulder joint and rotator cuff in the setting of a long-standing rotator cuff injury that does not involve
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SB203580 Modulates p38 MAPK Signaling and Dengue Virus-Induced Liver Injury by Reducing MAPKAPK2, HSP27, and ATF2 Phosphorylation.

... which SB203580 protects against liver injury during DENV infection in vivo, within the complex immune response, need further investigation. Therefore, we further investigated the role of SB203580 in controlling the symptom of DENV-induced liver injury and clarified the molecular mechanism by which SB203580 controls liver injury in a Balb/c mouse model of ... a high viral load. The molecular mechanism of DENV-induced liver injury is still under investigation. The mitogen activated protein kinases (MAPKs), including p38 MAPK, have roles in the hepatic cell apoptosis induced by DENV. However, the in vivo role of p38 MAPK in DENV-induced liver injury is not fully understood. In this study, we investigated the ... modulation of downstream signaling to p38 MAPK by SB203580 reduces the DENV-induced liver injury. Discussion Balb/c mice are susceptible to DENV infection and offer a convenient in vivo model of it [11– 13]. An intravenous injection of DENV was used to study liver injury in Balb/c mice [11–13] because it produces prominent symptoms compared to DENV-infected
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Myocardial Ablation of G Protein-Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic Pathway.

... at least after ischemic injury. Whether this is actually a GPCR-dependent process remains to be addressed. However it is clear that the loss of GRK2 expression can lead to increased Akt activation after I/R injury and this limits ischemic injury in the heart. It is well documented that Akt improves myocardial survival after I/R injury by inhibiting apoptotic ... of Cardiomyocyte GRK2 Reduces Post-I/ R Myocardial Injury To determine whether reduced GRK2 levels improve cardiac function by directly protecting heart against myocardial I/R injury PLOS ONE | www.plosone.org 4 June 2013 | Volume 8 | Issue 6 | e66234 Lowering GRK2 Protects Heart against I/R Injury Figure 4. Cardiac GRK2 KO Mice have Reduced ... myocardial infarction. Further, we have recently shown that when GRK2 expression is increased in the heart, as seen with cardiac stress, significantly more severe ischemic injury is seen after I/R injury [25]. The mechanism by which GRK2 promotes cell death in the heart is not fully understood as it appears to be associated with increased apoptosis due to reduced
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Rapid Screening of MDR-TB in Cases of Extra Pulmonary Tuberculosis Using Geno Type MTBDRplus.

... Extra Pulmonary Tuberculosis 15. Gurung R, Bhattacharya SK, Pradhan B, Gurung S, Singh Y. Phenotypic characterisation and drug sensitivity testing of mycobacteria isolated from extrapulmonary tuberculosis. Kathmandu Univ Med (KUMJ). 2010; 8(29):57–61. 16. Sachdeva R, Gardre DV, Talwar V. Characterization and drug susceptibility patterns of extrapulmonary ... Type MTBDRplus assay test was 48 hours. PLOS ONE | DOI:10.1371/journal.pone.0159651 July 21, 2016 1 / 10 Geno Type MTBDRplus in Extra Pulmonary Tuberculosis Conclusion The problem of MDR in extra pulmonary tuberculosis (EPTB) cannot be overlooked and due attention on patients should be given. Routine use of Geno Type MTBDRplus assay for the ... people and 0.4 million among HIV-positive people), while an estimated 190 000 people died of MDR-TB in the year 2015 as reported by WHO [1]. Though Pulmonary TB is the most common presentation of the disease, extra pulmonary TB (EPTB) is also emerging as a serious clinical problem, accounting for 15– 20 per cent of all the cases of tuberculosis and the percentage
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Using of Tendinous Plasty in Treatment of Patients with Flexor Tendons of 2–5 Fingers Injury in “Critical” Zone

... M.A. Shcerbakov, A.V. Zaretskov, et al. Using of Tendinous Plasty in Treatment of Patients with Flexor Tendons of 2–5 Fingers Injury in “Critical” Zone. Saratov Journal of Medical Scientific Research, 2009, vol. 5, № 2, p. 248–250. Injury of both superficial and deep tendons of fingers flexors needs to carry out tendinous plasty with excision of distal ... кафедра травматологии и ортопедии, кандидат медицинских наук. E-mail: obeydik@yandex.ru USING OF TENDINOUS PLASTY IN TREATMENT OF PATIENTS WITH FLEXOR TENDONS OF 2–5 FINGERS INJURY IN “CRITICAL” ZONE O.V. Beidik — Saratov State Medical University, Department of Traumatology and Orthopaedics, Professor, Doctor of Medical Science; M.A. Shcerbakov —
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Chronic obstructive pulmonary disease Assessment Test na avaliação de pacientes com doença pulmonar obstrutiva crônica em reabilitação pulmonar: há relação com nível de dispneia nas atividades de vida diária e com índice preditor de mortalidade? Estudo tr

... Pulmonary Disease Assessment Test na avaliação de pacientes com doença pulmonar obstrutiva crônica em reabilitação pulmonar: há relação com nível de dispneia nas atividades de vida diária e com índice preditor de mortalidade? estudo transversal Chronic Obstructive Pulmonary Disease Assessment Test in assessing of patients with chronic obstructive pulmonary ... Brunetto AF, Pitta F. Validation of the Modified Pulmonary Functional Status and Dyspnea Questionnaire and the Medical Research Council scale for use in Brazilian patients with chronic obstructive pulmonary disease. J Bras Pneumol. 2008;34(12):1008-18. 11. ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories. ATS statement: ... version of the London Chest Activity of Daily Living Scale (LCADL) in chronic obstructive pulmonary disease patients. Rev Port Pneumol. 2008;14(1):27-47. 6. Dodd JW, Hogg L, Nolan J, Jefford H, Grant A, Lord VM, et al. The COPD assessment test (CAT): response to pulmonary rehabilitation. A multicentre, prospective study. Thorax. 2011;66(5):425-9. 7.
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Cor triatriatum sinister and secondary pulmonary arterial hypertension in a dog.

... esquerdo, doença vascular pulmonar ABSTRACT This paper describes the occurrence of cor triatriatum sinister, a rare cardiac malformation in dogs, associated with pulmonary edema and pulmonary hypertension in a 5-year-old Poodle female with history of acute dyspnea and cyanosis. The animal presented acute respiratory failure, heart failure with low ... membrane, absence of structural abnormalities of the mitral valve and thickening of pulmonary artery tunica media associated with renal tubular degeneration. The occurrence of cor triatriatum in dogs is most common in the right atrium, defined as cor triatriatum dexter. Additionally, pulmonary arterial hypertension associated with this malformation is described ... defect. Keywords: congenital heart defect, left atrium, pulmonary vascular disease REFERÊNCIAS ADIN, D.B.; THOMAS, W.P. Balloon dilation of cor triatriatum dexter in a dog. J. Vet. Int. Med., v.13, p.617-619, 1999. AKINTUNDE, A.A. Cor triatriatum in an 86year-old woman: initial presentation with pulmonary hypertension discovered during preoperative
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