Equilibrium and kinetic study on chromium (VI) removal from simulated waste water using gooseberry seeds as a novel biosorbent
... Environ. Sci. Manage., 1(3): 233-244, Summer 2015 ISSN 2383 - 3572 Equilibrium and kinetic study on chromium (VI) removal from simulated waste water using gooseberry seeds as a novel biosorbent *J. Aravind; G. Sudha; P. Kanmani; A.J. Devisri; S. Dhivyalakshmi; M. Raghavprasad Department of Biotechnology, Kumaraguru College of Technology, Coimbatore 641049, ... functional groups such as hydroxyl, ester, amino, carboxyl, carbonyl, sulphydryl, and phosphor group to which heavy metal bind. In this context, Gooseberry seed powder (Phyllanthus acidus), a novel biosorbent was examined for Cr(VI) binding efficiency. In the present study, various parameters which influence Cr(VI) removal such as pH, initial metal ion concentration, contact ... th ed.American Public Health Association, Washington DC. Aravind, J.; Shanmugaprakash, M.; Sangeetha, H.S.; Lenin, C.; Kanmani, P., (2013). Pigeon pea (Cajanus cajan) pod as a novel eco-friendly biosorbent: a study on equilibrium and kinetics of Ni(II) biosorption, Int. J. Ind. Chem., (4): 25 (9 pages). Bajpai, A.K.; Rai, L., (2010). Removal of chromium
Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors.
... potently suppress the phosphorylation of DYRK1A substrates in cultured cells. PLOS ONE | DOI:10.1371/journal.pone.0132453 July 20, 2015 2 / 18 Novel β-Carboline DYRK1A Inhibitors Results and Discussion Kinase selectivity of the novel β-carboline DYRK1A inhibitors An extensive panel of new harmine analogs was designed and synthesized in order to develop a new ... Germany * email@example.com Abstract OPEN ACCESS Citation: Rüben K, Wurzlbauer A, Walte A, Sippl W, Bracher F, Becker W (2015) Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors. PLoS ONE 10(7): e0132453. doi:10.1371/journal.pone.0132453 Editor: Yann Herault, IGBMC/ICS, FRANCE Received: ... harmine is a high affinity inhibitor of DYRK1A but suffers from the drawback of inhibiting monoamine oxidase A (MAO-A) with even higher potency. Here we characterized a series of novel harmine analogs with minimal or absent MAO-A inhibitory activity. We identified several inhibitors with submicromolar potencies for DYRK1A and selectivity for DYRK1A and
Inhibition of mesothelin as a novel strategy for targeting cancer cells.
... and morphological alterations. Therefore, we propose the inhibition of Mesothelin as a potential novel strategy for targeting human malignancies. Citation: Wang K, Bodempudi V, Liu Z, Borrego-Diaz E, Yamoutpoor F, et al. (2012) Inhibition of Mesothelin as a Novel Strategy for Targeting Cancer Cells. PLoS ONE 7(4): e33214. doi:10.1371/journal.pone.0033214 Editor: ... well as designing novel therapeutic strategies for cancer therapy. proper maintenance of its biological functions. Our data in all studied cancer models show that a significant loss of viability follows the loss of MSLN expression. In light of this, MSLN can be rendered as suitable candidate for drug therapy with focus on finding novel small molecule ... Inhibition of Mesothelin as a Novel Strategy for Targeting Cancer Cells Kun Wang1., Vidya Bodempudi2., Zhengian Liu1, Emma Borrego-Diaz1, Farnaz Yamoutpoor1, Anna Meyer2, Richard A. Woo3, Weihong Pan1, Arkadiusz
Botulinum Toxin as a Novel Addition to Anti-Arthritis Armamentarium
... American Journal of Immunology 1 (2): 94-95, 2005 ISSN 1553-619X © 2005 Science Publications Botulinum Toxin as a Novel Addition to Anti-Arthritis Armamentarium Hamid Namazi and Zahra Majd Department of Orthopedic Surgery, Shiraz University of Medical Sciences, Iran Abstract: Osteoarthritis
Novel gut-based pharmacology of metformin in patients with type 2 diabetes mellitus.
... effects due to gut-based pharmacology which might provide insights into novel therapeutic approaches to treat T2DM and associated metabolic diseases. Trial Registration:: www.ClinicalTrials.gov NCT01357876 Citation: Napolitano A, Miller S, Nicholls AW, Baker D, Van Horn S, et al. (2014) Novel Gut-Based Pharmacology of Metformin in Patients with Type 2 Diabetes Mellitus. ... Novel Gut-Based Pharmacology of Metformin in Patients with Type 2 Diabetes Mellitus Antonella Napolitano1*, Sam Miller2, Andrew W. Nicholls3, David Baker3, Stephanie Van Horn4, Elizabeth ... resulted in only women completing all the study procedures. While we cannot rule out significant gender differences in the metformin effects we describe, it is our belief that these novel insights into the pharmacology of metformin justify further investigation with larger numbers of subjects, especially to determine whether there are subgroup differences
A Novel Method to Test Dependable Composed Service Components
... International Journal of Computer Networks & Communications (IJCNC) Vol.8, No.3, May 2016 A NOVEL METHOD TO TEST DEPENDABLE COMPOSED SERVICE COMPONENTS Khaled Farj1 and Adel Smeda2 1 Faculty of Science, University of Al-Jabel Al-Gharbi, P.O. Box 64200, Gharian, Libya 2 Faculty
Normosmic congenital hypogonadotropic hypogonadism due to TAC3/TACR3 mutations: characterization of neuroendocrine phenotypes and novel mutations.
... fsX23 PTC/TP novel TACR3 c.689 G.A R230H no novel TACR3 c.738-1 G.A Y247L fsX4 PTC/TP reported in ref. 3 TACR3 c.799 T.A Y267N decrease MAPK activity novel TACR3 c.824 G.A W275X PTC/TP recurrent in ref. 4 TACR3 c.857 A.G K286R no recurrent (rs2276973) TACR3 c.918 G.A M306I no novel TACR3 c.1003 C.T Q335X PTC/TP novel TAC3 c.209-1 ... B and NK3R receptor dysfunction can help to decipher the pathophysiology of this signaling pathway. Objective: To evaluate the prevalence of TAC3/TACR3 mutations, characterize novel TACR3 mutations and to analyze neuroendocrine profiles in nCHH caused by deleterious TAC3/TACR3 biallelic mutations. Results: From a cohort of 352 CHH, we selected 173 nCHH ... Voican A, Amazit L, Trabado S, et al. (2011) Normosmic Congenital Hypogonadotropic Hypogonadism Due to TAC3/TACR3 Mutations: Characterization of Neuroendocrine Phenotypes and Novel Mutations. PLoS ONE 6(10): e25614. doi:10.1371/journal.pone.0025614 Editor: Manuel Tena-Sempere, University of Córdoba, Spain Received June 24, 2011; Accepted September
Synaptic metaplasticity underlies tetanic potentiation in Lymnaea: a novel paradigm.
... Synaptic Metaplasticity Underlies Tetanic Potentiation in Lymnaea: A Novel Paradigm Anita Mehta1*, Jean-Marc Luck2, Collin C. Luk3, Naweed I. Syed3 1 S. N. Bose National Centre for Basic Sciences, Calcutta, India, 2 Institut de Physique Théorique, ... Gif-sur-Yvette, France, 3 Hotchkiss Brain Institute, Faculty of Medicine, University of Calgary, Alberta, Canada Abstract We present a mathematical model that explains and interprets a novel form of short-term potentiation, which was found to be use-, but not time-dependent, in experiments done on Lymnaea neurons. The high degree of potentiation is explained using ... model of a stochastic and bistable biological switch. Citation: Mehta A, Luck J-M, Luk CC, Syed NI (2013) Synaptic Metaplasticity Underlies Tetanic Potentiation in Lymnaea: A Novel Paradigm. PLoS ONE 8(10): e78056. doi:10.1371/journal.pone.0078056 Editor: Michel Baudry, Western University of Health Sciences, United States of America Received July 31,
A Novel Algorithm for Improving the ESP Game
... (IJACSA) International Journal of Advanced Computer Science and Applications, Vol. 4, No. 9, 2013 A Novel Algorithm for Improving the ESP Game Mohamed Sakr Department of Computer Science Faculty of Computers and Information, Menoufia University Shebin El-Kom, Egypt Hany
Novel Anti-Nicotine Vaccine Using a Trimeric Coiled-Coil Hapten Carrier.
... RESEARCH ARTICLE Novel Anti-Nicotine Vaccine Using a Trimeric Coiled-Coil Hapten Carrier Keith D. Miller¤, Richard Roque, Christopher H. Clegg* TRIA Bioscience Corp, Seattle, Washington, United ... *firstname.lastname@example.org ¤ Current address: Affinogen Bioscience, LLC, Moscow, Idaho, United States of America Abstract OPEN ACCESS Citation: Miller KD, Roque R, Clegg CH (2014) Novel Anti-Nicotine Vaccine Using a Trimeric Coiled-Coil Hapten Carrier. PLoS ONE 9(12): e114366. doi:10.1371/journal.pone. 0114366 Editor: Geetha P. Bansal, Tulane University, ... each monomer of the TCC. In summary, we have developed two important tools that could significantly improve the performance of anti-addiction vaccines in people. The first is a novel synthetic hapten carrier and the second is the adjuvant GLA-SE, which was far superior to Alum in augmenting anti-nicotine Ab titer, affinity, and function. This is consistent
Correction: Establishment of a Canine Rabies Burden in Haiti through the Implementation of a Novel Surveillance Program.
... High Canine Rabies Burden in Haiti through the Implementation of a Novel Surveillance Program. The correct citation is: Wallace RM, Reses H, Franka R, Dilius P, Fenelon N, Orciari L, et al. (2015) Establishment of a High Canine Rabies Burden in Haiti through the Implementation of a Novel Surveillance Program. PLoS Negl Trop Dis 9(11): e0004245. doi:10.1371/journal.pntd.0004245 Reference 1. ... the Implementation of a Novel Surveillance Program. PLoS Negl Trop Dis 9(11): e0004245. doi:10.1371/journal.pntd.0004245 PMID: 26600437 OPEN ACCESS Citation: Wallace RM, Reses H, Franka R, Dilius P, Fenelon N, Orciari L, et al. (2016) Correction: Establishment of a Canine Rabies Burden in Haiti through the Implementation of a Novel Surveillance Program. ... CORRECTION Correction: Establishment of a Canine Rabies Burden in Haiti through the Implementation of a Novel Surveillance Program Ryan M Wallace, Hannah Reses, Richard Franka, Pierre Dilius, Natael Fenelon, Lillian Orciari, Melissa Etheart, Apollon Destine, Kelly Crowdis, Jesse
Novel marmoset (Callithrix jacchus) model of human Herpesvirus 6A and 6B infections: immunologic, virologic and radiologic characterization.
... Novel Marmoset (Callithrix jacchus) Model of Human Herpesvirus 6A and 6B Infections: Immunologic, Virologic and Radiologic Characterization Emily Leibovitch1,2., Jillian E. Wohler1., ... further define the contribution of this ubiquitous virus to human neurologic disorders. Citation: Leibovitch E, Wohler JE, Cummings Macri SM, Motanic K, Harberts E, et al. (2013) Novel Marmoset (Callithrix jacchus) Model of Human Herpesvirus 6A and 6B Infections: Immunologic, Virologic and Radiologic Characterization. PLoS Pathog 9(1): e1003138. doi:10.1371/journal.ppat.1003138 Editor: ... serologic responses. HHV-6 DNA is found in MS lesions   . Moreover, HHV-6 PLOS Pathogens | www.plospathogens.org 1 January 2013 | Volume 9 | Issue 1 | e1003138 Novel Marmoset Model of HHV6A and HHV6B Infections Author Summary The human herpesviruses HHV-6A and HHV-6B are widely distributed in the human population, but also specifically
Variable myopathic presentation in a single family with novel skeletal RYR1 mutation.
... Variable Myopathic Presentation in a Single Family with Novel Skeletal RYR1 Mutation Ruben Attali1., Sharon Aharoni2., Susan Treves3., Ori Rokach3, Michal Becker Cohen1, Yakov Fellig4, Rachel Straussberg2, Talya Dor5, Muhannad Daana5, ... h = 0.0 and homozygosity of the polymorphic markers at this locus in patients. Direct sequencing of the main candidate gene within the candidate region, RYR1, was performed. A novel homozygous A to G nucleotide substitution (p.Y3016C) within exon 60 of the RYR1 gene was found in patients. ARMS PCR was used to screen for the mutation in all available ... Ca2+ stores. Western blot analysis demonstrated a significant reduction of the RyR1 protein in the patient’s muscle concomitant with a reduction of the DHPRa1.1 protein. This novel mutation resulting in RyR1 protein decrease causes heterogeneous clinical presentation, including slow progression course and absence of centrally localized cores on muscle
A Novel Approach for Re-Narrating Web Pages in Multicasting Networks
... International Journal of Innovations in Engineering and Technology (IJIET) A Novel Approach for Re-Narrating Web Pages in Multicasting Networks Dr. K Rameshwaraiah Professor Dept of CSE Prof N. Hari Babu Professor Dept of CSE Abstract - “Designing
A Novel Admixture-Based Pharmacogenetic Approach to Refine Warfarin Dosing in Caribbean Hispanics.
... JY, et al. (2016) A Novel Admixture-Based Pharmacogenetic Approach to Refine Warfarin Dosing in Caribbean Hispanics. PLoS ONE 11(1): e0145480. doi:10.1371/journal.pone.0145480 Editor: Min-Han Tan, Institute of Bioengineering and Nanotechnology, SINGAPORE Received: August 1, 2015 Abstract Aim This study is aimed at developing a novel admixture-adjusted ... RESEARCH ARTICLE A Novel Admixture-Based Pharmacogenetic Approach to Refine Warfarin Dosing in Caribbean Hispanics Jorge Duconge1☯*, Alga S. Ramos1☯, Karla Claudio-Campos2, Giselle Rivera-Miranda3, ... proportions. Fostered by an urgent need to eliminate potential ethnic disparities in health care while implementing the personalized medicine paradigm, this study is aimed at developing a novel admixture-adjusted pharmacogenomic approach to predict individual maintenance doses of warfarin, after the fourth day of therapy (refinement model), in Caribbean Hispanic
A novel whole-cell mechanism for long-term memory enhancement.
... A Novel Whole-Cell Mechanism for Long-Term Memory Enhancement Iris Reuveni, Drorit Saar, Edi Barkai* Departments of Neurobiology and Biology, University of Haifa, Haifa, Israel Abstract Olfactory-discrimination ... than the number of channels and thus has the potential to be readily induced and un-induced by whole-cell transduction mechanisms. Citation: Reuveni I, Saar D, Barkai E (2013) A Novel Whole-Cell Mechanism for Long-Term Memory Enhancement. PLoS ONE 8(7): e68131. doi:10.1371/ journal.pone.0068131 Editor: Benjamin Arenkiel, Baylor College of Medicine, United
A novel interaction between plant-beneficial rhizobacteria and roots: colonization induces corn resistance against the root herbivore Diabrotica speciosa.
... A Novel Interaction between Plant-Beneficial Rhizobacteria and Roots: Colonization Induces Corn Resistance against the Root Herbivore Diabrotica speciosa Franciele Santos1, Maria ... protection of corn against the South American corn rootworm, D. speciosa, is considered. Citation: Santos F, Pen˜ aflor MFGV, Pare´ PW, Sanches PA, Kamiya AC, et al. (2014) A Novel Interaction between Plant-Beneficial Rhizobacteria and Roots: Colonization Induces Corn Resistance against the Root Herbivore Diabrotica speciosa. PLoS ONE 9(11): e113280. ... beans (Phaseolus spp.) and soybeans (Glycine max (L.) Merrill) . The larval stage lives in PLOS ONE | www.plosone.org 1 November 2014 | Volume 9 | Issue 11 | e113280 Novel Interaction between Rhizobacteria and Roots the soil and is usually found in corn roots, where its development is optimal compared with in other crop plants . Considering
Novel method for isolation of murine clara cell secretory protein-expressing cells with traces of stemness.
... mice. Accordingly, the novel method described herein is a significant step in the progress of isolating and characterizing highly purified Clara cells in primary cultures. Based on previous publications, the distribution of CCSP expression in non-ciliated Clara cells is described as cytoplasmic [23,24,25]. We made the surprising and novel discovery of ... discovery of CCSP immunoreactivity in plasma membranes of airway lining cells prompted us to explore the possibility of enriching Clara cells by flow cytometry. We established a novel and simple method for the isolation of CCSP-expressing cell Clara cells using a combination of mechanical and enzymatic dissociation followed by flow cytometry sorting technology. ... method for investigating the function of primary Clara cells in stem cell research and mouse models. Citation: Wang X-Y, Keefe KM, Jensen-Taubman SM, Yang D, Yan K, et al. (2012) Novel Method for Isolation of Murine Clara Cell Secretory Protein-Expressing Cells with Traces of Stemness. PLoS ONE 7(8): e43008. doi:10.1371/journal.pone.0043008 Editor: Vladimir
Identification of Novel Variants in LTBP2 and PXDN Using Whole-Exome Sequencing in Developmental and Congenital Glaucoma.
A Novel Cache Resolution Technique for Cooperative Caching in Wireless Mobile Networks
... 7, Issue 11, 525 – 527(2003).  Yi-Wei Ting ,Yeim-Kuan Chang. A novel cooperative caching scheme for wireless ad hoc networks: Group caching. In NAS ’07: Proceedings of the International Conference on Networking, Architecture,and Storage,( 2007).  S Lim, WC Lee, G Cao, CR Das, A novel caching scheme for improving Internet-based mobile ad hoc networks ... existing cache to make way for new ones. In this paper we focus on cache placement and resolution. Towards the goal of improving the performance in cooperative cache, we propose a novel cache resolution scheme which uses a split table approach to resolve the cached data request which in turn reduces latency and message overhead. More precisely, our algorithm ... A NOVEL CACHE RESOLUTION TECHNIQUE FOR COOPERATIVE CACHING IN WIRELESS MOBILE NETWORKS Preetha Theresa Joy1 and K. Poulose Jacob2 1,2Department of Computer Science, Cochin University
Discovery and computer aided potency optimization of a novel class of small molecule CXCR4 antagonists.
... Volume 8 | Issue 10 | e78744 Discovery of a Novel Class of CXCR4 Antagonists Figure 1. Structures of TN14003, AMD3100, AMD3465, AMD11070, and GSK812397. doi: 10.1371/journal.pone.0078744.g001 In view of the significant role that CXCR4 activation plays in cancer and other diseases, identification of novel small molecule antagonists, which would ... 2013 | Volume 8 | Issue 10 | e78744 Discovery of a Novel Class of CXCR4 Antagonists Figure 3. A view of the residues surrounding the binding pocket of CXCR4. doi: 10.1371/journal.pone.0078744.g003 PLOS ONE | www.plosone.org 6 October 2013 | Volume 8 | Issue 10 | e78744 Discovery of a Novel Class of CXCR4 Antagonists Figure 4. Preparation ... | e78744 Discovery of a Novel Class of CXCR4 Antagonists Figure 13. Relationship between pIC50 in the calcium flux assay and the calculated free energy of binding (ΔG) to CXCR4. doi: 10.1371/journal.pone.0078744.g013 PLOS ONE | www.plosone.org 14 October 2013 | Volume 8 | Issue 10 | e78744 Discovery of a Novel Class of CXCR4 Antagonists Figure
Apolipoprotein J/Clusterin is a novel structural component of human erythrocytes and a biomarker of cellular stress and senescence.
... erythrocytes. In the present report we provide novel evidence showing that sCLU distributes in RBCs cytosol and membrane and that its relative content during senescence or in diseases closely correlates to the expression of typical cellular senescence, erythrophagocystosis and oxidative stress markers. Our novel findings clearly imply a functional role ... membrane-associated sCLU in the splenectomised patient HS-1 most probably relates to a decreased release of sCLU-containing vesicles. Taken together, our results provide novel evidence for an emerging role of sCLU, a novel structural component of RBCs plasma membrane and cytosol, in the physiology of mature human erythrocytes. The erythrocytes sCLU content decreases ... sensitive biomarker of senescence and cellular stress. Citation: Antonelou MH, Kriebardis AG, Stamoulis KE, Trougakos IP, Papassideri IS (2011) Apolipoprotein J/Clusterin Is a Novel Structural Component of Human Erythrocytes and a Biomarker of Cellular Stress and Senescence. PLoS ONE 6(10): e26032. doi:10.1371/journal.pone.0026032 Editor: Roger Chammas,
Machado de Assis em graphic novel: adaptação ou tradução?
... 220.127.116.11. Graphic Novels _________________________________________________ 31 18.104.22.168. Graphic novels baseadas em obras literárias __________________________ 35 1.2. O que é literatura? ______________________________________________________ 37 1.3. Quadrinhos como Literatura? _____________________________________________ 43 1.4. Graphic novels baseadas ... Machado de Assis, no formato graphic novel. A questão fundamental para o desenvolvimento do estudo concerne ao tratamento dado a essas transposições, com o objetivo de analisar os processos que delas decorrem. Com base em vários estudos, como os de McCloud, Ramos e Eisner, buscou-se compreender a natureza híbrida das graphic novels, assim como a importância ... em muitas das graphic novels analisadas, esta pesquisa interroga o campo da formação de leitores e de professores, no sentido da construção de uma competência leitora que irá auxiliar os profissionais a lidar com esse material já disponível no ambiente escolar. Palavras-chave: Texto Literário – História em quadrinhos – Graphic Novel – Adaptação – Tradução
SYNTHESIS, CRYSTAL STRUCTURE AND MAGNETIC BEHAVIOUR OF NOVEL 4f-2s HETEROMETALIC ONE-DIMENSIONAL COORDINATION POLYMERS ON THE BASE OF 2-FURAN-CARBOXYLIC ACID
... Chemistry Journal of Moldova. General, Industrial and Ecological Chemistry. 2009, 4 (2), 60-67 SYNTHESIS, CRYSTAL STRUCTURE AND MAGNETIC BEHAVIOUR OF NOVEL 4f-2s HETEROMETALIC ONE-DIMENSIONAL COORDINATION POLYMERS ON THE BASE OF 2-FURAN-CARBOXYLIC ACID Silvia Melnica, Denis Prodiusa,*, Sergiu Shovab, Helen Stoeckli-Evansc, Yurii ... mechanism on the involvement of the f orbital in magnetic interactions, but also for understanding chemical properties, and application of rare earth metal for the synthesis of novel molecular magnets [1-3]. However, the research on molecular materials with lanthanides up to now was mostly focused on the interaction of transition metal with lanthanide