Bioactive Compounds

The use of L-ascorbic acid in speciation of arsenic compounds in drinking water

... investigated on three channels system with peristaltic pump (HVG-1) for hydride generation. Through the channel for the sample aspiration, water solutions of arsenic compounds or solutions of arsenic compounds with hydrochloric acid, L-ascorbic acid or KI were introduced. Hydrochloric acid was introduced through the second channel and through the third channel ... L-ascorbic acid or easier approach of the pre-reducing agent (KI) to methylated arsenic compounds. It is evident that in the process of reduction agent iodine was made and it was reduced with L-ascorbic acid into iodide, which entered into the process of reduction of arsenic compounds again. The detailed conclusions about the L-ascorbic acid influence could ... speciation can be very important in the analysis of water, foodstuffs, and environmental samples, besides of total arsenic analysis. Possible method used in the speciation of arsenic compounds is atomic absorption spectrometry with hydride generation, and it is based on the generation of certain types of hydride, depending on the pH value and pretreatment in
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Modeling of RO/NF membrane rejections of PhACs and organic compounds: a statistical analysis

... fifteen compounds. Scores on the Com pon ent score 1 x-axis (component 1) may indicate the overall level of rejecFigure 2. Component scores for compounds Figure 2. Component scores for compounds tion, while scores on the y-axis indicate possibly differences Figure 2. Component scores for compounds. between compound properties. Clustering of compounds classified ... discussion Rejection of compounds by membranes Table 3 presents results of rejection for compounds corresponding to the membranes with which the experiments were carried out. All results are from samples taken after 48 hours of experimental running. Two membrane types were selected for experiments with all compounds: LE-440 (RO) and NF90 (NF). 4.2 PCA for compounds ... dissociation constant, compounds with a pKa greater than 7 or not available (N/A) pka were selected as neutral, otherwise were ionic, this classification is related to acidity of waters, our ionic compounds dissociate at pH 8. In our case the pKa of all our compounds is less than 7; though the ionic species were dissociated at pH 8. Compounds were classified
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Study of the effect of surfactants on extraction and determination of polyphenolic compounds and antioxidant capacity of fruits extracts.

... surfactants are amphiphilic compounds and have the ability to producing various micellar phases in aqueous and organic solutions, make them marvelous compound in extraction of various compounds. According to these abilities they can solved various hydrophilic and hydrophobic compounds in themselves micellar phases. Phenolics compounds consist of various ... researches and applications of plant polyphenols [9,10]. Phenolic compounds represent a large group of chemical substances with a variety of functions in plant growth, development, and defense. Phenolic compounds include signaling molecules, pigments and flavors that can attract or repel, as well as compounds that can protect the plant against insects, fungi, bacteria, ... lowering incidences of cancer and cardiovascular diseases. A concern of the widespread use of phenolic compounds is the estrogenic activity these compounds may display, which impacts the hormone balance and may result in breast cancer in women. Moreover, phenolic compounds have an important role in the nutritional, organoleptic and commercial properties of agricultural
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Bioactive Triterpenes from the Fungus Piptoporus betulinus

... of bioactive metabolites. The responsible bioactive compounds belong to several chemical groups, very often they are polysaccharides or triterpenes [1]. Mushrooms need antibacterial and antifungal compounds to survive in their natural environment. It is therefore not surprising that antimicrobial compounds are reported from mushrooms and that these compounds ... peroxide (7), and fomefficinic acid (9), were also isolated from the fungus. All isolated compounds were tested for antimicrobial activity against some Gram-positive and Gramnegative bacteria as well as against a fungal strain. The new triterpene and some of the other compounds showed antimicrobial activity against Gram-positive bacteria. Keywords: Piptoporus ... subjected to solid phase extraction (C18-E cartridges and MeOH/H2O gradient). The obtained fractions were then separated by preparative HPLC to yield eleven compounds. The structural identification of the compounds was performed by spectroscopic methods as described in the next section. 2.4 . Antimicrobial assays The antimicrobial tests were carried out
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Evaluating the bioactive effects of flavonoid hesperidin: A new literature data survey

... Strana 60 VOJNOSANITETSKI PREGLED GENERAL REVIEW Vojnosanit Pregl 2014; 71(1): 60–65. UDC: 615.322::616.1-084 DOI: 10.2298/VSP1401060K Evaluating the bioactive effects of flavonoid hesperidin – A new literature data survey Ocena bioaktivnih efekata flavonoida hesperidina – pregled podataka iz novije literature Vesna Kuntiü*, ... retrospective of some basic data about flavonoids, their pharmacological properties and mechanism of action. In this review, special attention was paid to one of the most promising bioactive bioflavonoids, hesperidin (Hesp). About flavonoids Flavonoids (flavus, the Latin word for yellow) or bioflavonoids, polyphenolic low weight secondary metabolites, Kljuÿne ... radioprotective agent (marketed by MedImmune under the trade name Ethyol®). However, due to its side effects and toxicity, the use of this drug should be replaced with less toxic natural compounds 68. Kuntiý V, et al. Vojnosanit Pregl 2014; 71(1): 60–65. Volumen 71, Broj 1 VOJNOSANITETSKI PREGLED Since much research has been focused on the potential use of
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Contribution of sulfuric acid and oxidized organic compounds to particle formation and growth

... condensation of organic compounds. Plotting growth rates due to organic compounds as a function of sulfuric acid concentration for partiAtmos. Chem. Phys., 12, 9427–9439, 2012 0 10 6 2 3 4 5 6 7 8 9 10 2 7 1 2 3 3 4 4 5 5 6 6 7 8 9 10 8 -3 [H2SO4] (cm ) Fig. 7. Initial growth rates attributable to organic compounds observed with ... acid. Indeed, our observations do not rule out the possibility that other compounds participate in the particle formation mechanism. The total concentration of organic precursors in a boreal forest is comparable to the α-pinene concentration used in these experiments, but other compounds may have been present as contaminants. A recent study (Kirkby et ... growth is further hindered by the broad family of condensable organic compounds that are formed during the time of the experiment, the temporal effect; i.e., while the particles grow to larger diameters both the chemical composition and the concentration of the condensable organic compounds change. A qualitative distinction between the temporal effect
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... Chemistry and application of phosphoorganic compounds. — М.: Nauka, 1982. — 286 p. 2. Afonskaya L. S., Zaikonnikova I. V. Biological activity of complex lipids of mono- and -dialkilphosphinic acids and their comparative characteristic. / Materials of the conference «Chemistry and application of phosphoorganic compounds ». - М., 1992. - P. 437-442. 3. ... 1263-1269. 9. Zeimal E. V., Mikhelson M. Ya., Frushtov N. K. On physiological activity of phosphoorganic compounds (the link between chemical composition and pharmacological activity // Materials of the conference «Chemistry and application of phosphoorganic compounds ». - М., 1992. – P. 403-422. 10.Novikov S. S., Schweitheimer T. A. Reaction of carbometoxy-methylentriphenylphosphine with aromatic ... SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME PHOSPHORCONTATNING ORGANIC COMPOUNDS CONTAINING Annals of Mechnikov Institute, N 3, 2013 /journal.htm 47 FRAGMENTS OF UREA AND TRYHLORETILAMIDU Gushylyk B. Data about directions of synthesis and use of the phosphororganic compounds in technics, biology and medicine is presented in the paper.
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Transcriptional response of zebrafish embryos exposed to neurotoxic compounds reveals a muscle activity dependent hspb11 expression.

... hspb11 toxic) compound and 2,4-dinitrophenol (DNP), an oxidative decoupling agent. The test compounds were selected to allow the identification of genes specifically responding to compounds inhibiting acetylcholine esterase. Neurotoxicity is a common MoA among compounds exhibiting an excess toxicity (i.e. ratio of predicted baseline toxicity versus measured ... assign mechanisms of action (MoA) to non-characterized or unknown compounds [4]. Changes in gene expression by exposure to chemicals can be directly inferred from binding of a compound to a transcription factor. Prominent examples are the aryl hydrocarbon or estrogen receptors. However, many compounds, e.g. neurotoxic chemicals, may not interfere directly ... lead to the identification of molecular mechanisms and specific marker genes for potential neurotoxic compounds. Citation: Klüver N, Yang L, Busch W, Scheffler K, Renner P, et al. (2011) Transcriptional Response of Zebrafish Embryos Exposed to Neurotoxic Compounds Reveals a Muscle Activity Dependent hspb11 Expression. PLoS ONE 6(12): e29063. doi:10.1371/journal.pone.0029063 Editor:
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... 13, Issue 4, 2013 PRINT ISSN 2284-7995, E-ISSN 2285-3952 POSSIBILITIES TO USE NATURAL EXTRACTS FROM MEDICINAL AND AROMATIC PLANTS (MAP) LIKE BOTANICAL REPELLENT OR INSECTICIDE COMPOUNDS AGAINST PEST INSECTS IN ECOLOGICAL CROPS (II) Irina IONESCU-MĂLĂNCUŞ1, Traian MANOLE2, Petru NICULIŢĂ1, Eugenia PETRESCU3 1 University of Agricultural Sciences and Veterinary ... increasing problems of insecticide resistance and increasing public concerns regarding pesticide safety, new, safer active ingredients are becoming necessary to replace existing compounds on the market. The present study carried out in the period 2010-2012 comprises a review of two insect repellents, followed by some new research conducted in our laboratory ... (Asterales:Asteraceae) and Delphinium consolida L. (Ranales:Ranunculaceae). The tests carried out in laboratory and field experimentally plots under cages permit to evaluate several other compounds for repellent activity of lacctucin alkaloids. Key words: alkaloids, biorational insecticide, repellents INTRODUCTION Biological resources and the potential for sustainable
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Integron gene cassettes and degradation of compounds associated with industrial waste: the case of the Sydney tar ponds.

... potentially encode more biochemical reactions involved in the degradation of compounds associated with industrial processes than those found collectively in the ,7000 cassettes sampled from other environments studied to date. The cassette-encoded catabolic enzymes that potentially degrade compounds associated with industrial processes like catechol 1,4-dioxygenase ... exposed for almost a century to products of coal and steel industries, has developed a rich and unique cassette metagenome, containing genes likely to aid in the catabolism of compounds associated with industrial waste found there. In addition, we report that the most abundant cassette recovered in this study is one that encodes a putative LysR protein. ... integron-meditated LGT likely to be important in natural bioremediation. Citation: Koenig JE, Sharp C, Dlutek M, Curtis B, Joss M, et al. (2009) Integron Gene Cassettes and Degradation of Compounds Associated with Industrial Waste: The Case of the Sydney Tar Ponds. PLoS ONE 4(4): e5276. doi:10.1371/journal.pone.0005276 Editor: Ching-Hong Yang, University of Wisconsin-Milwaukee,
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The effect of lanthanides on color properties of the (Bi2O3)0.7(Ln2O3)0.3 compounds

... properties. From this point of view just compounds on the base of Bi2O3 belong to pigments of oxide types and seem to be interesting, because they provide interesting colour hues from yellow to orange [2]. Intense colours of these pigments are based on the incorporation of doped Ln3+ ions into the host lattice of Bi2O3. These compounds produce not only interesting ... makes that their colour becomes lighter. 4. Conclusion The compounds (Bi2O3)0.7(Ln2O3)0.3, where Ln = Eu, Gd, Tm, Yb and Lu, were synthesized. The presence of these rare earth cations makes interesting hue of prepared samples and at the same time contributes to increase of their thermal stability. Compounds containing Yb, Lu and Tm provide intensive orange ... Journal of Journal of Mining and Metallurgy 44 B (2008) 27 - 33 Mining and Metallurgy THE EFFECT OF LANTHANIDES ON COLOUR PROPERTIES OF THE (Bi2O3)0.7(Ln2O3)0.3 COMPOUNDS P. Šulcová and E. Proklešková Department of Inorganic Technology, Faculty of Chemical Technology University of Pardubice, Legions Sq. 565, 532 10 Pardubice, Czech Republic Dedicated
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Production of bioactive soluble interleukin-15 in complex with interleukin-15 receptor alpha from a conditionally-replicating oncolytic HSV-1.

... cells. The purpose of these studies was to engineer an oHSV producing bioactive IL-15. Two oHSVs were constructed encoding murine (m)IL-15 alone (J100) or with the mIL-15 receptor α (mIL-15Rα, J100D) to determine whether co-expression of these proteins is required for production of bioactive mIL-15 from oHSV. The following were demonstrated: i) both ... was responsible. Given the complexity of mIL-15 and mIL-15Rα association and trafficking, it is notable that bioactive mIL-15/IL-15Rα was produced in the presence of virally induced cellular stress. PLOS ONE | Production of bioactive mIL-15/IL-15Rα provides a foundation for future investigation with this oHSV. To our knowledge, the ... cytotoxicity, demonstrating soluble mIL-15/IL-15Rα complex production from J100D was independent of direct oHSV effects. iv) The soluble mIL-15/ IL-15Rα complex produced by J100D was bioactive, stimulating NK cells to proliferate and reduce the viability of syngeneic GL261 and CT-2A cells. v) J100 and J100D were aneurovirulent inasmuch as no neuropathologic
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[3+2] Cycloadditions of 1-halo-1-nitroethenes with (Z)-C-(3,4,5-trimethoxyphenyl)-N-methyl-nitrone as regio- and stereocontrolled source of novel bioactive compounds: preliminary studies

... products. Additionally, prognosis for the synthesized compounds to be potential ingredients of drugs is good. © 2016 Growing Science Ltd. All rights reserved. 1. Introduction Isoxazolidines are an important class of bioactive compounds. 1-3 The presence of the nitro group in the molecule of these compounds stimulate extra forms of biological activity ... [3+2] Cycloadditions of 1-halo-1-nitroethenes with (Z)-C-(3,4,5-trimethoxyphenyl)-N-methyl-nitrone as regio- and stereocontrolled source of novel bioactive compounds: preliminary studies Radomir Jasińskia*, Ewa Dreslerb, Maria Mikulskaa and Daniel Polewskia aInstitute of Organic Chemistry and Technology, Cracow University ... to adducts with a nitro group at C4 position of the isoxazolidine ring. Finally, we have decided to diagnose a potentially interesting bioactivity properties of the synthesized compounds. For this purpose we have used PASS simulation program, which has recently been successfully applied to a design of a number of medicines 22. It has been found (Table
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A low-cost, hands-on module to characterize antimicrobial compounds using an interdisciplinary, biophysical approach.

... growth media, and antimicrobial compounds used are listed in Table 1 along with the associated references [19–27]. Briefly, we used Escherichia coli DH5 a, a commercial broth, and eucalyptus oil, ethanol, and hydrogen peroxide as antimicrobial compounds. Table 1. Bacterial strain, media conditions, and antimicrobial compounds. Bacterial strain E. ... antimicrobial compounds. This opened a brief discussion on recent efforts towards exploring natural, biological, and indigenous resources as antimicrobial agents [6–9]. Importantly, this overview emphasized the key feature of our laboratory module, whereby an interdisciplinary approach could aid the discovery and identification of novel antimicrobial compounds, ... Text). We used the disc diffusion assay to test the antimicrobial activity of different compounds [11, 12], a technique used in clinical and research microbiology laboratories to study the bacterial and fungal strains’ susceptibility to antibiotics [13, 14]. In the assay, compounds to be tested for antimicrobial activity are deposited on filter discs that
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Elemental ratio measurements of organic compounds using aerosol mass spectrometry: characterization, improved calibration, and implications

... Phys., 15, 253–272, 2015 doi:10.5194/acp-15-253-2015 © Author(s) 2015. CC Attribution 3.0 License. Elemental ratio measurements of organic compounds using aerosol mass spectrometry: characterization, improved calibration, and implications M. R. Canagaratna1, J. L. Jimenez2, J. H. Kroll3,4, Q. Chen3, S. H. Kessler4, ... however, with larger biases observed for alcohols and simple diacids. A detailed examination of the H2O+, CO+, and CO2+ fragments in the high-resolution mass spectra of the standard compounds indicates that the Aiken-Ambient method underestimates the CO+ and especially H2O+ produced from many oxidized species. Combined AMS–vacuum ultraviolet (VUV) ionization ... present in ambient Published by Copernicus Publications on behalf of the European Geosciences Union. 254 M. R. Canagaratna et al.: Elemental ratio measurements of organic compounds OA. For ambient OA, the Improved-Ambient method produces O : C (H : C) values that are 27 % (11 %) larger than previously published Aiken-Ambient values; a corresponding
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Volatile organic compounds in the western Mediterranean basin: urban and rural winter measurements during the DAURE campaign

... Copernicus Publications on behalf of the European Geosciences Union. The Cryosphere Open Access cess M 4292 R. Seco et al.: Volatile organic compounds in the western Mediterranean basin compounds (VOCs). The first results of the campaign have recently been published (e.g. Minguillo´n et al., 2011; Moreno et al., 2011; Seco et al., 2011b; ... isoprene: methyl vinyl ketone and methacrolein); (ii) short-chain oxygenated compounds (oxVOCs, see Seco et al., 2007 for a review): methanol, acetone, acetaldehyde, acetic acid and ethanol; (iii) aromatic volatiles: benzene, toluene, and C8 aromatics (a term that includes compounds such as xylenes); and (iv) acetonitrile. All VOC mixing ratios are ... doi:10.5194/acp-13-4291-2013 © Author(s) 2013. CC Attribution 3.0 License. Atmospheric Chemistry and Physics Open Access Atmospheric Measurement Techniques Volatile organic compounds in the western Mediterranean basin: Open Access urban and rural winter measurements during thBeioDgeAoUscRieEncceasmpaign R. Seco1,2,*, J. Pen˜ uelas1,2, I.
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... Gold to medicinal gold (either Swarna Bhasma or Gold compounds; chemical entity of conventional system) is an exemplary example of promising potentials of Pharmaceutical branches of both system of medicines. In this review paper an assortment of facts about clinical application of Swarna Bhasma and Gold compounds have been congregated from both system of ... Singh Neetu et al / IJRAP 3(1), Jan – Feb 2012 Review Article SWARNA BHASMA AND GOLD COMPOUNDS: AN INNOVATION OF PHARMACEUTICS FOR ILLUMINATION OF THERAPEUTICS Singh Neetu*, Chaudhary Anand Department of Rasa Shastra, Faculty of Ayurveda, Institute of Medical ... considered by modern science and they are using gold in various chemical forms in therapeutics as well as diagnostics. Although constituency, mode of action of Swarna Bhasma and gold compounds may be different but ultimate objectives of both medicinal form of gold is same i.e prevention and cure of diseases for better life. GOLD IN TRADITIONAL SYSTEM OF MEDICINE
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Inactivation of the antibacterial and cytotoxic properties of silver ions by biologically relevant compounds.

... Inactivation of the Antibacterial and Cytotoxic Properties of Silver Ions by Biologically Relevant Compounds Geraldine Mulley1*, A. Tobias A. Jenkins2, Nicholas R. Waterfield3 1 School of Biological Sciences, University of Reading, Reading, United Kingdom, 2 Department of ... conditions, particularly the type of growth media used in vitro. The toxicity of Ag+ to bacterial cells is comparable to that of human cells. We demonstrate that biologically relevant compounds such as glutathione, cysteine and human blood components significantly reduce the toxicity of silver ions to clinically relevant pathogenic bacteria and primary human ... antimicrobial silver coatings. Citation: Mulley G, Jenkins ATA, Waterfield NR (2014) Inactivation of the Antibacterial and Cytotoxic Properties of Silver Ions by Biologically Relevant Compounds. PLoS ONE 9(4): e94409. doi:10.1371/journal.pone.0094409 Editor: Andrew C. Marr, Queen’s University Belfast, United Kingdom Received February 17, 2013; Accepted March
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Fractions of cell wall nitrogenous compounds in tropical forages.

... detergente neutro. ABSTRACT The total and undegradable fractions of nitrogenous compounds associated to cell wall organic matrix in some tropical forages were evaluated. Samples of corn silage, elephantgrass silage and sugarcane were used. Neutral detergent insoluble nitrogenous compounds were divided in three different fractions associated with: hemicellulose ... rumen. The heterogeneous dimensions of degradable portion of all nitrogenous compounds among feeds can compromise the estimates of cell wall undegradable nitrogen by simple chemical approaches in tropical forages. The LN overestimated the lignin contents and the correction for those compounds on lignin has been suggested. Keywords: rumen, degradability, ... n.1, p.258-263, 2007 Comunicação [Communication] Frações dos compostos nitrogenados associados à parede celular em forragens tropicais [Fractions of cell wall nitrogenous compounds in tropical forages] L.T. Henriques1,3, E. Detmann2,4*, A.C. Queiroz2,4, S.C. Valadares Filho2,4, M.I. Leão2, M.F. Paulino2,4 1Aluno de pós-doutorado - UFV, MG
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