Tools For Assessment
Description and implementation of a MiXed Layer model (MXL, v1.0) for the dynamics of the atmospheric boundary layer in the Modular Earth Submodel System (MESSy)
... yields a computationally inexpensive tool that is ideally suited for the analysis of field data, for evaluating new parametrizations for 3-D models, and for performing systematic sensitivity analyses. A case study for the DOMINO campaign in southern Spain is shown to demonstrate the use and performance of MXL/MESSy in reproducing and analysing field observations. 1 Introduction In ... accounting for boundary layer growth and ABL-FT exchange. As for scalars, the inclusion of reactive species requires the introduction of two additional equations for each species. The expression for the evolution of the generic species C is similar to that for potential temperature (Eq. 1) and moisture (Eq. 7), but includes a term for the chemical transformation (Vilà-Guerau ... important for calculating surface–atmosphere exchange, and appears for instance in the calculations of the aerodynamic resistance which governs evapotranspiration (Sect. 2.7.2) and dry deposition. Similar expressions as for hθ i and hqi can be used for the two horizontal components of the wind speed. These equations also contain the Coriolis force that
Downregulation of blood-brain barrier phenotype by proinflammatory cytokines involves NADPH oxidase-dependent ROS generation: consequences for interendothelial adherens and tight junctions.
... dose-dependent increase in protein expression for both gp91 (up to 2.1-fold for both cytokines at 100 ng/ml) and p47 (up to 3.5-fold and 3.0-fold at 100 ng/ml of TNF-a and IL-6, respectively) (Figure 6A). In further experiments, cells were treated with 100 ng/ml of either TNF-a or IL-6 for 18 hrs before being harvested for analysis of gp91/p47 co-association ... 5% CO2/95% air at 37uC. For experimental purposes, cells were routinely subjected to treatment with either TNF-a or IL-6 at 0–100 ng/ml (0–24 hrs), concentration ranges routinely used in other papers [10,19]. Postcytokine treatment, cells were harvested for analysis. For cell lysate preparation, cells were washed thrice in PBS before being scraped into ... agents. Confluent HBMvECs were pre-treated with either SOD, CAT, NAC or APO before being treated with 100 ng/ml of either TNFa or IL-6 for up to 18 hrs, after which cells were harvested and monitored for ROS production by flow cytometry (necessitating cell pre-labelling with ROS-sensitive CFDA) or for protein expression analysis by Western blotting. Pre-treatment
Relationship between Interleukin-6 gene polymorphism and hippocampal volume in antipsychotic-naive schizophrenia: evidence for differential susceptibility?
... Additionally, Voxel-based Morphometry (VBM) analysis was performed using hippocampal mask. The IL-6 level was measured in blood plasma using ELISA technique. SNP rs1800795 was genotyped using PCR and DNA sequencing. Psychotic symptoms were assessed using Scale for Assessment of Positive Symptoms and Scale for Assessment of Negative Symptoms. Results: Schizophrenia ... 10). Excellent reliability was ascertained with intra-class correlation coefficient of more than 0.95. Assessment of Positive Symptoms (SAPS) and Scale for Assessment of Negative Symptoms (SANS). Healthy controls (N = 37) (age = 27.465.6 years; 20-males), who volunteered for study, were screened to rule out any psychiatric diagnosis using the MINI as well as a ... neurological/medical disorder. None had abnormal movements as assessed by Abnormal Involuntary Movements Scale. Clinical assessments and blood sample collection were performed on the same day before starting antipsychotics. After complete description of study to the subjects, written informed consent was obtained. The research protocol was reviewed and approved by the National Institute
Social Network for Scientists with a Focus on ResearchGate
... Elsevier se oslanja na svoju bazu Scopus. Znanstvenici mogu dodavati podatke i oblikovati svoj profil. Institucije zastupljene na ovoj platformi mogu se izravno povezati u društvenu mreÞu Vivo. Ovo je komercijalna platforma koja ima besplatno dostupan dio Biomedexperts * Sofija Konjeviæ, e-pošta: firstname.lastname@example.org (www.biomedexperts.com), koji povezuje ... laboratorija, omoguæuje razmjenu ideja, poruka, slika, protokola putem profila, foruma, bloga. Sci-mate (www.sci-mate.org/index.php) – Scientific Material Transfer Environment – namijenjen razmjeni ideja, radova i drugih zanimljivih “artikala”. U sebi ujedinjuje elemente wikija, e-baya, foruma i društvene mreÞe. Ovo su samo neke od mreÞa namijenjenih znanstvenicima, ... 3. 2013.). 2. Connect portal. URL: http://portal.connect.znanost.org (21. 3. 2013.). 3. M. J. Coren, A New Social Network For Science Could Change How We Make Discoveries. URL: http://www.fastcoexist.com/1679977/a-new-social-network -for- science-cou ld-change-how-we-make-discoveries (20. 3. 2013.). 4. S. Gajiæ, J. Stankoviæ, D. Laliæ, B. Miliæ, Uloga društvenih
Robust network topologies for generating switch-like cellular responses.
... for studying how switching can arise in natural systems and as a design tool for engineering switch-like behavior in synthetic circuits. Author Summary Biomolecular signaling networks enable cells to mediate responses to extracellular and intracellular stimuli and are hence crucial for the functioning of all organisms. Such networks do not merely forward ... A acts as an enzyme activator for C, and B is effectively a background inactivator for both A and C (since there are no incoming links for B). When the total concentration (inactive and active) of C is much greater than those of active A (k1 zk2 ) , see and B, and the effective Michaelis constant (K~ k0 Methods) values for activation and inactivation ... were constructed and simulated; response profiles were used to compute robustness scores for ultrasensitivity and bistability for each network topology. This process was repeated for each compositional class. Histograms depict the distribution of robustness scores for ultrasensitivity and bistability greater than 1% across all compositional classes; white
Parallel Implementation of Bias Field Correction Fuzzy C-Means Algorithm for Image Segmentation
... neighbors effect as mentioned in  for low-SNR images). To evaluate our implementation, we compared its performance to a sequential equivalent. For this purpose, runtime for serial execution was measured on the host processor that was obtained from single-core execution and referenced (TABLE.I). The GPU based computing duration for the same experiment parameters ... the maximum speed-up is achieved for the GTX 580 that is almost 5x faster than GT 740M and 2.5x faster than GTX 760. The speed-ups reached for this figure are 52x, 20x and 13x for GTX 580, GTX 760 and GT 740 respectively for image size up to about to 7 Mega pixels. According to our study, it seems clear that the performance speed-up depends on the strength ... we conducted is clearly manifested for large image sizes. This is validated experimentally for different tests and different GPU cards. This study shows another aspect on performance analysis in terms of data storage effect on the performance of each card (data exchange inside memory card). Another aspect of GPU performance can be sorted out by inspecting
Hematoma shape, hematoma size, Glasgow coma scale score and ICH score: which predicts the 30-day mortality better for intracerebral hematoma?
... with written informed consent waived, recruited 106 patients diagnosed as ICH by non-enhanced computed tomography study. The hemorrhagic shape, hematoma size measured by computer-assisted volumetric analysis (CAVA) and estimated by ABC/2 formula, ICH score and GCS score was examined. The predicting performance of 30-day mortality of the aforementioned ... was used for 2-group comparisons regarding parameters with normal distribution, while nonparametric tests (Wilcoxon signed rank tests and McNemar tests) were used for 2-group comparisons regarding parameters without normal distribution. Linear regression analysis was used to assess the relationship between the hematoma size estimated by ABC/2 formula ... (P,0.032), GCS score (P,0.001), and ICH score (P,0.001). Location of hematomas The 30-day mortality was 23.1% (3 of 13) for infratentorial hematomas and was 14.0% (13 of 93) for supratentorial hematomas. The difference between the aforementioned locations, however, was not statistically significant (P = 0.391). Patients with pontine hematomas had a
Benefits of Either Operative or Non-Operative Treatment for Perilunate Dislocation and Fracture Dislocations
... fixation.Mil Med. 2011;176(9):107782. 6. Kremer T, Wendt M, Riedel K, Sauerbier M, Germann G, Bickert B. Open reduction for perilunate injuries-clinical outcome and patient satisfaction. J Hand Surg Am. 2010;35(10):1599-606. 7. Forli A, Courvoisier A, Wimsey S, Corcella D, Moutet F. Perilunate dislocations and transscaphoid peri- lunate fracture-dislocations: ... Mayo wrist score, Grip strength, range of motion and radiographic parameters. It seems that the results were comparable to studies by Capo, Chou, Laporte, Malovic, Kremer, Forli and Lutz (Table 1) (2-8). In the studies listed above, all the patients were treated by operative fixation and none of them reported any experience with non-operative treatment ... (5) 2011 Croatia Op. PLFD 43 29 m 87 Kremer et al (6) 2010 Germany Op. Op. PLD PLFD 9 30 66 m 70 20 77° 70% Op. PLD 11 13 y 77 13 Forli et al (7) 2010 France Op. PLFD 7 13 y 74 35 8 94° 4 98° 87% 87% Lutz et al (8) Op. PLD 15 2009 Austeria Op. PLFD 10 5y 5y 81.5 20.7 82.7
One-Class FMRI-Inspired EEG Model for Self-Regulation Training.
... work, different models were constructed for different subjects. In this work, we carefully analyzed the inhomogeneity among subjects and were able to construct a single model for the majority of the subjects. We introduce a method for inhomogeneity assessment. This enables us to demonstrate a choice of subjects for which a single model could be derived. ... (e.g. feed-forward neural network ). The transformation steps before applying the metric are shown in Fig 1. These include: converting their frequency bands on the y-axis to a single frequency band division by expanding their y-axes to a minimum resolution of 1Hz and collapsing this back to a uniform frequency band division. The uniform frequency ... (fatigue, motivation), particularly in task-oriented experiments. Therefore, this adaptation cannot be automatically performed. Fig 5a depicts the performance of the individual model constructed for the first session when testing on the second session. The figure focuses on subjects for whom their first session was included in the common model construction
The semianalytical cloud retrieval algorithm for SCIAMACHY I. The validation
... DFG BU 688/8-1 and BMBF 07 GWK 04 Projects. We are grateful to J. Joiner (NASA) for providing data for Fig. 10 (ATSR-2 and GOME/LER) in a tabular form. European Space Agency, the UK Natural Environment Research Council and the Rutherford Appleton Laboratory are acknowledged for their support in supplying ATSR-2 and GOME data. Edited by: U. Platt References Bovensmann, ... have been performed for spherical polydispersions with the effective radius of 6 microns and the gamma size distribution of particles having the coefﬁcient of variance equal to 38 percent, which is typical for water clouds. The change of the scattering optical thickness with the wavelength was neglected, and we assumed that it is equal to 10 for all wavelengths. The ... The Advanced Along Scanning Radiometer(AATSR) on board of the ENVironmental SATellite (ENVISAT) should provide additional information (e.g., independent measurements of cloud top temperature). Unfortunately, the processing schemes for all instruments onboard ENVISAT are currently decoupled, which is mostly due to the complexity of integration of the cloud
Discrete Cosine Transform-II for Reduction in Peak to Average Power Ratio of OFDM Signals Through μ-Law Companding Technique
... amount ofcompression. 4. DISCRETE COSINE TRANSFORM-II The discrete cosine transforms (DCT) is a Fourier-related transform similar to the discrete Fourier transform (DFT). It is a member of a family of sinusoidal unitary transforms. This transform is real, orthogonal and separable with fast algorithms for its computation. They have abetter job ... forward combination of two existing techniques namely -Law Companding Transform and Discrete Cosine Transform-II precoding technique. The simulation results show that, the proposed combinedscheme gives better result for PAPR Reduction and results in no distortion. Keywords FDM, FDM, PAPR, FFT, IEEE, DCT, CCDF 1. INTRODUCTION As the demand for ... DCT-II precoded signal. 7. CONCLUSIONS In this paper, a new idea about the performance of the µ-Law companding technique combined with precoded technique is presented for the reduction of PAPR value. The PAPR value can be reduced for different modulation formats and for different values of M by using proposed 154 International Journal of Wireless
The effects of backward adjustable thoracic support in wheelchair on spinal curvature and back muscle activation for elderly people.
... systems for consumers, clinicians, and manufacturers. Further research is necessary to discover the optimal backward degree for BTS and the optimal period for regulating the backward and forward alternation of the BTS during prolonged sitting. Acknowledgments The authors are very grateful to Cho-Lin Wang, Chih-Hsien Chen, and Ting-Wei Huang for technical ... that reclined backrest, forward tilted seat, and lumbar support can help reduce lumbar load [13, 14]. However, a reclined backrest may disrupt the functional sitting posture and may cause the user to slide forward, thus generating an undesirable sitting posture [15, 16]. Using a forward tilted seat risks causing the user to slide forward when moving the ... pelvic angle were observed. The BTS posture appeared to yield significantly higher values for pelvic angle (P,0.001) and lower values for lumbar angle (P50.014) when compared with the LSS posture. No significant differences in thoracic angle were observed, except for the NS versus the BTS, The latter posture appeared to yield significantly higher values
A mechanism for chronic filarial hydrocele with implications for its surgical repair.
... signed the inform consent form. For each individual, information regarding the hydrocelectomy technique used was retrospectively gathered from the patient’s medical records. All included, consenting individuals underwent physical and ultrasound examinations of the scrotal area. Group-2 (G2) Patients from CG who underwent hydrocelectomy at NEPAF for hydrocele ... been performed in any family member. The family member(s) identified for previous hydrocelectomy was/were invited to NEPAF and selected according the following inclusion criteria: (1) if they lived in a house where at least one person had been positive for Wuchereria bancrofti microfilaria in the blood, (2) if they had had hydrocelectomy performed between ... NEPAF. Patients were selected using the following criteria: (a) aged between 18 and 40 year-old at the time of surgery and had signed the inform consent forms, which included permission to use his medical information for scientific publication; (b) documented uni- or bilateral hydrocele by physical examination (inspection and bimanual palpation) and ultrasonography
Europium nanoparticle-based high performing immunoassay for the screening of treponemal antibodies.
A tool for assessing the usefulness of prevalence studies done for surveillance purposes: the example of hypertension
... concentrate on the essential aspects of assessment. THE ASSESSMENT MODEL Our instrument for assessing a scientific report or article contains 19 questions covering six technical aspects: • • • • • • declared objectives the population under study sampling design methods for gathering information the processing of the information communicating the results The ... provide information that, in spite of being static, involves past data and points toward areas that may require further attention. In the second place, prevalence studies may be the source of baseline information on which to base future assessments of changing patterns by means of measurements performed over time. Thirdly, they are useful for quantitatively ... by correcting estimates for which not all subjects had the same chance of being in the sample, as tends to be the case when a more or less uniform sample size is used despite the fact that the age pyramid is not uniform for all ages. Attributing the unweighted sample prevalence to the entire population is an error in such cases. For example, let’s suppose
HIV/STD transmission in gold-mining areas of Bolivar State, Venezuela: interventions for diagnosis, treatment, and prevention
... the categories of participants. Sera were screened for antibodies against HIV and HTLV I/II by enzyme immunoassay (EIA), and double reactive specimens were confirmed by Western blot for HIV and both Western blot and immunofluorescence for HTLV I/II. For syphilis a specific hemagglutination method was used, and for HBV a high-sensitivity MicroELISA test was ... babies at the Tumeremo hospital commented that almost all women giving birth deliver infants infected with gonorrhea (19). For logistical reasons it was impossible for Contrasida to include testing for gonorrhea in this HIV/STD effort since that would have required access to a medical setting in order to be able to take The Ministry of Health of Venezuela ... University of Venezuela for processing the blood samples. Special thanks also go to the executive personnel of Placer Dome for their moral and financial support. Contrasida thanks all the community leaders in the gold-mining area for their wholehearted support. Lastly, we thank Dr. Yon Fleerackers of the Tropical Institute of Antwerp for his support in designing
International guiding principles for biomedical research involving animals
... and use before, during, or after experimentation. They may be established by specific legislation laying down standards and providing for enforcement by an official inspectorate; by more general legislation requiring biomedical research institutions to provide for peer review in accordance with defined principles and criteria, sometimes with informed lay ... an urgent need for basic and applied research that will lead to the discovery of methods for the prevention and treatment of diseases for which adequate control methods are not yet available-notably the noncommunicable diseases and the endemic communicable diseases of warm climates. Past progress has depended, and further progress in the foreseeable future ... prelude to experimental trials on human beings of, for example, new therapeutic, prophylactic, or diagnostic substances, devices, or procedures. There are two international ethical codes intended principally for the guidance of countries or institutions that have not yet formulated their own ethical requirements for human experimentation: the Tokyo revision of
The moral meaning of religion for bioethics
... death could be put into context and more readily approached from the direction of already-formed convictions about respect for the individual’s integrity and his or her body, care and treatment for the dying, a demand for equity in the provision of health care, and a concern for including the socially voiceless and vulnerable within the boundaries of the moral community. This ... treatment conforms to this principle because it typically benefits a patient. The principle of justice obligates one to ensure that the benefits of health care (or in some cases the burdens, such as taxes for hospitals) are distributed fairly and equitably. For example, the benefits of experimental research on human beings can be inestimable for many people, ... and equality must be in the forefront of our moral universe. Moreover, these traditions understand all human beings to be created in the irnage of God (imago Dei); and this imago Dei concept not only reinforces a sense of commonality and equality but also respect for individual autonomy. Thus, moral norms with profound meaning for religious traditions
CD29.R12: Topic for the technical discussions to be held in 1986
... COMMITTEE Washington D.C., 26 September – 3 October 1983 RESOLUTION CD29.R12 TOPIC FOR THE TECHNICAL DISCUSSIONS TO BE HELD IN 1986 THE 29th DIRECTING COUNCIL, Mindful that the 90th Meeting of the Executive Committee recommended "Workers' Health"1 as the topic for the Technical Discussions in 1985: Having decided (Resolution VI) that Technical Discussions ... Discussions are to be held only in even years; and Desirous that Technical Discussions be held on so important a subject, RESOLVES To declare "Workers' Health" selected as the topic for the Technical Discussions to be held in 1986 during the XXII Pan American Sanitary Conference. Sept.–Oct. 1983 OD 192, 57
CD25.R3: Request of the Government of Grenada for membership in the PAHO
... THE REGIONAL COMMITTEE Washington D.C., 27 September – 6 October 1977 RESOLUTION CD25.R3 REQUEST OF THE GOVERNMENT OF GRENADA FOR MEMBERSHIP IN THE PAHO THE 25th DIRECTING COUNCIL, Having examined the formal request for membership in the Pan American Health Organization made on behalf of the Government of Grenada by the Ministry of External Affairs ... Code, as amended by the Additional Protocol of 24 September 1952, and to contribute by means of a quota assessment to the financial support of the Organization, RESOLVES 1. To approve with satisfaction the request by the Government of Grenada for membership in the Pan American Health Organization. 2. To instruct the Director to transmit this decision
Diabetes mellitus: a challenge for the countries of the region
... Caribbean area (WFuture Prospects Control of the diabetes problem requires an organized effort by all the countries of the Region. As a first step, consideration should be given to establishing an adequate registration system that would provide a basis for planning control programs. Programs of primary prevention, except for obese subjects, are hard to envisage at present. On the ... problem in the Region over the next 10 to 15 years. Programs for the control of diabetes mellitus should include educational campaigns for patients, the public, and health professionals; early detection of the disease in high-risk groups; reglstration and followup of cases and the organization of systems for providing comprehensive care. Promotion of basic, ... all causes) has merely doubled (4). Many countries of the Region possess little information on the prevalence of diabetes. Furthermore, in most cases the studies that are available do not reflect the real magnitude of the problem, due to difficulties of interpretation. For example, a study by Poon-King, et al., in Trinidad (5) showed an overall prevalence
Request of the Government of the Commonwealth of the Bahamas for membership in the PAHO
... AMERICANHEALTH CSP19/13 (Eng.) 30 July 1974 ORIGINAL: ENGLISH OF THE COMMONWEALTH ORGANIZATION OF THE BAHAMAS FOR MEMBERSHIP The Director of the Pan American Sanitary Bureau is pleased to inform the Conference that he has received a request from the Government of the Commonwealth of The Bahamas for membership in the Pan American Health Organization. The Director brought this ... EXECUTIVE COMMITTEE, Having examined the formal request for membership in the Pan American Health Organization made by the Minister of External Affairs of the Commonwealth of The Bahamas on behalf of his Government, in a letter dated 26 February 1974, RESOLVES: i. To take note of the request of the Commonwealth of The Bahamas for membership in Organization, and ... examined the formal request for membership in the Pan American Health Organization made by the Minister of External Affairs of the Commonwealth of The Bahamas on behalf of his Government, in a letter dated 26 February 1974, (Eng. CE72/12 Page 2 RESOLVES : i. To take note of the request of the Government of the Commonwealth of The Bahamas for membership in
Proposed program and budget estimates of the WHO for the region of the Americas for 1978-79
... 1974 ORIGINAL: ENGLISH PROPOSED PROGRAM AND BUDGET ESTIMATES OF THE WORLD THE REGION OF THE AMERICAS FOR 1978-79 HEALTH ORGANIZATION FOR The Director-General of the World Health Organization has requested that the Regional Committee for the Americas recommend a tentative program projection in global terms for 1978 and 1979, within a planning ceiling of US$12,744,000 and $13,445,000, respectively. The ... Health Organization for the Region of the Americas for 1976 and 1977; and needs Recognizing the advisability into future years, of projecting probable program RESOLVES: To recommend to the Director General that he include in the Program and Budget Estimates of the World Health Organization for 1978 and 1979 the proposed program for the Region of ... been made taking into account trends in programs and priorities for such additional resources as may become available in this Region. The Regional Committee may wish to recommend this distribution to the Director-General of the World Health Organization for inclusion in the WHO program for 1978-79 by adopting a resolution along the following lines: THE
Report on buildings and installations for headquarters
... was -seen with the completion of the framework for the second level and the laying of the concrete slab. This holds all the conduits for :the simultaneous interpretation. equipment and the necessary.' steel plates .for the placement of the conference tables and :chairs for the three conference chambers. Framing for the third floor is progressing and it is ... foundation work has been completed, including the placement of 112 caissons of reinforced concrete placed on bedrock, at an average depth of 52 feet below the sub-basement. The concrete for the sub-basement and basement has been poured and forms have been set for pouring concrete for the street level slabs. The work by plumbers, steamfitters, and electricians has ... was given to the members for their information and study and it was agreed that the Subcommittee would be convened at 10:00 a.m.,Thursday, 17 September 1964 for further discussion and decision on the sale. Upon the Chairman's request for additional business the Director addressed the Committee and spoke on the matter of gifts for the new building from
Closing the ranks for health for all
... continent. I am referring not only to what you receive, whether as concepts that have given rise to the new health paradigm for attaining health for all by the year 2000, or in very practical terms through international support, for example for such initiatives as Carribean Cooperation in Health. I am also referring to what you give to others in other parts ... permanent health infrastructure based on primary health care, in order to attain health for all. For my part, desiring to compensate for the difficult regular budget situation, I have stretched my moral conscience to the limit in attempts to secure extrabudgetary funds for that purpose. I now appeal to you to stretch your imagination to the limit to make ... if we are to reach our goal of health for all by the year 2000 and keep it up afterwards. So even if others may have lost faith in us, we must preserve our faith by demonstrating that it is well founded, by always keeping in front of us our health value system, by persevering in our policy and strategy for health for all, and by using collective resources